ANTIANXIETY PROPERTY OF TECOMA STANS LINN LEAVES EXTRACT IN EXPERIMENTAL ANIMALS - OBJECTIVES

 

2. OBJECTIVES

 

            The review of literature reveals that antianxiety activity of Tecoma stan linn leaves has not been reported. In view of this, the present study is aimed to investigate the antianxiety activity of the Tecoma stan linn leaves with the following objectives:

 

1.       Identification and authentication of the plant material.

2.       Extraction of Tecoma stan linn leaves with suitable solvents, such as petroleum ether, chloroform, ethanol and water.

3.       To carryout preliminary phytochemical analysis of crude extracts for the detection of the type of phytoconstituents present.

4.       To study the acute toxicity for determination of LD₅₀ of the extract in female albino mice.

5.       To evaluate the effect of Tecoma stan linn leaves extract for the antianxiety property in mice and rats in following models:-

a)      Elevated Plus-Maze test in mice.

b)      Hole-board test in rats.

c)      Light-dark model transition test in mice.

d)     Open field test in mice.